FPV Centrifugal Pump
Centrifugal Pump with advanced Seal technology for pharmaceutical process
The Fristam FPV Centrifugal Pump with advanced seal technology; double seal flush, C-cooling, and diamond seal works for pharmaceutical and biopharmaceutical processing. Engineered for high-pressure WFI (water for injection) & high-purity pharmaceutical applications. Types of Pharmaceutical Pumps comply with the ASME BPE (Bioprocessing Equipment), CE, 3A and EHEDG compliant design standards to enhance product purity and reduce contamination risk.
For pharmaceutical applications, the FPV centrifugal pump is available with three advanced mechanical sealing options, which depend upon operating temperature, process fluid, sterility requirement and cleaning methods. The seal options serve a different purpose. The pressurised double-seal flush systems that maintain positive pressure in the critical seal area to ensure product sterility and prevent flashing. The front seal flush is a recirculation loop which saves valuable products. The internal seal design provides extra cooling and lubrication on the front seal face to significantly extend seal life and enhance system uptime. The typical pharma applications are APIs, sterile formulations, solvents, and crystallised products and FDA compliant with passivated and tested for sterile application.
Then, another advanced seal technology is C-cooling, which cools the mechanical seal to prevent overheating, a unique Balanced Design, multi-coil springs and a pusher-type seal. Designed for Hot water application with API Plan 11 and built-in hydrodynamic feature. It ensures a liquid film between the faces, which helps to minimize wear and ultimately to achieve long seal life. Applications for C-cooling include hot CIP solutions, heated syrup transfer, hot purified water, heated chemicals, and temperature-sensitive media.
With the diamond seal option, the seal faces are specially made with a unique diamond face coating. It acts as a single mechanical seal that is extremely hard and war-resistant and exhibits low friction and excellent heat conductivity. No external cooling is required under normal conditions. Typical applications include WFI (water for injection), purified water, RO water, ethanol, IPA, low-viscosity buffers, and CIP buffers.
Technical Specifications
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14 different sizes
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System pressures up to 25 bar
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Discharge pressures up to 15 bar
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Flow rates up to 550 m3/h
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Viscosities up to 800 mPa.s
Specific Construction
Every Fristam FPV centrifugal pump uses a casing drain built alongside multiple mounting options, giving pumps with 100% drainability, which matters most for keeping the system validated-clean over the long run. This design pairs with CIP (clean-in-place) and SIP (steam-in-place) sterilization capability, so external cooling equipment becomes unnecessary between batches. That combination keeps validation cycles shorter and operating costs more predictable across multi-shift production.
Being a hygienic centrifugal pump at its core, the FPV Pharma Pump series works well with sterile fluids that are sensitive to shear or contamination risk. Material of construction stands with stainless steel 316L (1.4404), 1.4435, 1.4462 or 1.4539, special MOC, Hastelloy or titanium with low delta ΔFe cont. <1% grade components covering the wetted parts for corrosion resistance. Using only these high-quality metals guarantees the best possible hygienic standards for operation in sensitive industries such as pharmaceuticals, biotechnology and cosmetics. That precision keeps contamination risk low and cuts down product loss on delicate biologics, something plants tend to notice within the first few validations runs. Low NPSHr value for customized compact skid design.
Application
Salient Features
Seal Options
Material of Construction
Mechanical Seal Materials
Surface Finishes
Elastomers
Seal Options
Seal Options
Fristam’s pressurized double-seal flush keeps the area protected and lasts much longer under demanding plant conditions. C-Cooling lowers seal temperature for hot pharmaceutical liquids, helping reduce wear over time. Diamond seal works without external cooling and fit WFI or purified water applications, delivering long service life while keeping maintenance requirements very low.Material of Construction
Material of Construction
Product-contact components are machined from 316L (1.4404), 1.4435, 1.4462 or 1.4539 stainless steel, with Hastelloy and titanium available for harsher process fluids. Fristam Pumps has trusted these grades since the early 1970s. That consistency is one reason plants call this one of the more dependable stainless steel pumps for sterile duty. Fristam offers the most comprehensive documentation package with complete traceability of all parts, including elastomers.Mechanical Seal Materials
Mechanical Seal Materials
Cast chrome, ceramic, silicon carbide, tungsten carbide or carbon are available for the mechanical seal, matched to whichever piping configuration a process needs, including single seal setups. Picking the right combination protects the seal face against abrasive or aggressive fluids. Get this wrong, and seal replacement turns into a recurring line item nobody budgeted for.Surface Finishes
Surface Finishes
Pharmaceutical pumps need very smooth surface finish to meet the hygiene standards of ASME BPE (bioprocessing equipment) design, and SF4 is often the expected finish. Fristam delivers that without cutting corners. Internal products with contact surface finish achieve Ra ≤ 0.38 µm through electropolishing which smooths and protects the stainless steel.External surfaces are CNC machined to reach nearly 0.8 Ra for a clean finish. Some sterile applications also require an SF1 mechanically polished finish with Ra ≤ 0.51 µm. The cleaning process includes degreasing, pickling, electropolishing, passivation, and a final hot DI water rinse. Every surface is inspected carefully before it leaves production.
Elastomers
Elastomers
USP Class VI elastomers ship standard on every pharmaceutical unit, meeting the baseline plants’ expectations for product contact surfaces. Perfluoroelastomers are available too, for processes running aggressive chemicals or higher temperatures, the standard grade won’t tolerate. Full traceability documentation comes with either option, tracked back to the raw material batch.Where the FPV Centrifugal Pump is used?
Fristam FPV series centrifugal pumps are used across sterile plant floors built for high-purity applications. A biopharmaceutical processing pump line uses it for WFI (water for injection) transfer, buffer prep and media movement, and as a sterile CIP system pump, it keeps validated cleaning cycles running between batches. Vaccine and biologics manufacturers pick it too, running it for shear-sensitive formulations that standard transfer pumps tend to damage.
Looking to buy an FPV centrifugal pump for your pharmaceutical processing? Explore the Fristam FPV Centrifugal Pump series to find the right hygienic solution for high-purity pharmaceutical applications. Contact our experts today to request a quote and choose the best centrifugal pump for your operation.
