A recent study conducted by Fristam Pumps has revealed how well the FDS Twin Screw Pump performs when it comes to handling sensitive fluids in pharmaceutical and life science sectors. The testing took place at the respected bioX Applications Lab in Salem, New Hampshire, a facility known for its in-depth physical, mechanical, biological, and chemical testing.
The goal was to see if the FDS pump could move delicate products gently and consistently, without causing damage or loss of quality.
The result was a simple and obvious answer. The pump delivered excellent results across all flow rates and pressures, with minimal mechanical shear, very low pulsation, and strong protection for delicate cells and proteins.

Key Highlights of the Study

  • Less than 5% hemolysis: After two hours of continuous pumping at different pressures, red blood cell damage was minimal, much lower than other pump types.
  • Only 4% protein loss: In Immunoglobulin G (IgG) tests, protein concentration dropped only slightly after one hour at 2 bar, showing excellent protein protection.
  • Smooth, steady flow: Very low pulsation ensures consistent, reliable performance, ideal for precise processes like chromatography and filtration.

What Makes it Special?

When compared with rotary lobe and peristaltic pumps, which often cause higher damage and loss, the FDS Twin Screw Pump stands out as a clear winner. It not only protects product quality but also improves efficiency and reliability in production.

Here’s what makes it different:
  • Multi-use versatility: Handles both product transfer and gentle CIP (Clean-in-Place) without needing separate pumps.
  • Wide operating range: Performs efficiently across a broad range of viscosities and flow rates, making it suitable for multiple production stages.
  • Low maintenance needs: Its robust design reduces wear and tear, cutting downtime and maintenance costs.
  • Hygienic design: Fully CIP/SIP-capable and compliant with strict industry sanitation standards.
  • Gentle on every product batch: Maintains integrity even during long production runs, ensuring batch-to-batch consistency.

Conclusion

The Fristam FDS Twin Screw Pump delivers gentle, consistent handling of sensitive fluids, making it ideal for pharmaceutical and life science applications requiring quality, efficiency, and precision.
Its ability to minimize shear forces, reduce hemolysis, and protect proteins ensures optimal results in processes like filtration, Tangential Flow Filtration (TFF), and chromatography.
Want to know more? Get the full insights — download the whitepaper now and see how the Fristam FDS can elevate your production performance.

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