Positive Displacement Pumps in Pharmaceutical Production: Ensuring Precise Fluid Control

January 24, 2024

Home Blog Positive Displacement Pumps in Pharmaceutical Production: Ensuring Precise Fluid Control

In the pharmaceutical sector, precision and accuracy are non-negotiables. The choice of pump in manufacturing processes plays a critical role. Which is why positive displacement pumps have emerged as a go-to: they're versatile, handling a diverse range of liquids, including those that are viscous or sensitive to shear.

In addition, they're outperforming other pump types in efficiency and reliability. In this blog, we're exploring the benefits of using positive displacement pumps in the pharma sector.

Read on to find out how they bring an edge to pharmaceutical manufacturing.

But before that, let’s quickly touch upon what a positive displacement pump is.

At its core, a positive displacement pump operates on a simple yet ingenious principle. It traps a fixed amount of fluid and then forces (displaces) that trapped volume into the discharge pipe. Unlike their counterparts, these pumps deliver a consistent flow at a constant speed, regardless of the pressure. This unique attribute makes them an ideal fit pump for the pharmaceutical industry, where precision and consistency are indispensable.

The Benefits of Positive Displacement Pump in Pharmaceutical Production

In pharmaceuticals, the use of positive displacement pumps offers several advantages:

  • Accuracy and Consistency: These pumps are necessary in pharmaceuticals to enable accurate dosing and formulation. They deliver a relatively constant fluid per cycle, providing precise control required to comply with the stringent dose demands in pharmaceuticals. This accuracy is especially crucial in processes such as tablet coating and syringe filling, as minor errors may impact the effectiveness and security of the product.
  • Handling Sensitive Fluids: These pumps are remarkably efficient in moving fragile pharmaceutical components. They preserve the structural integrity of fragile fluids, like biologics subjected to shear forces or environmental temperature changes.
  • Hygienic Operation: These pumps are engineered to ensure your pharmaceutical products are contaminant-free. They are especially used for operations calling for strict sanitation procedures and are easy to clean. These features frequently enable SIP or CIP, both of which are essential for pharmaceutical manufacturing sanitation.
  • Adaptability: The ability of these pumps to handle a wide range of fluid viscosities makes them highly useful for various pharmaceutical processes. Whether dealing with thin, water-like solutions or thick, viscous gels, positive displacement pumps can efficiently move these materials without compromising the flow rate or causing damage. This versatility is invaluable in an industry that deals with a wide spectrum of formulations, from liquid drugs to ointments and creams.

Critical Role in the Pharmaceutical Industry

In pharmaceutical manufacturing, positive displacement pumps have a multifaceted role, supporting the process from start to finish. Their consistent delivery of flow and pressure is crucial for the quality and effectiveness of the end products. These pumps aid in precise drug dosing and efficient fluid transfer.

These pumps meet high regulatory standards and help minimize contamination risks.

Choose Fristam Pumps

At Fristam Pumps, we bring over a century of expertise to the forefront in providing positive displacement pumps for the pharmaceutical industry. We design our pumps to meet the essential demands for precision, hygiene, and adaptability in this critical field. Our proven track record makes us a dependable choice for pharmaceutical companies looking for fail-safe pumping solutions.

Choosing Fristam means partnering with a century of excellence in advancing pharmaceutical production technology. Connect with us today to learn how our pumps can elevate your operations.


1) What is the role of positive displacement pumps in pharmaceutical production?

Positive displacement pumps in pharmaceutical production move various fluids throughout the manufacturing process. They ensure accurate and consistent fluid transfer, which is vital for dosing, formulation, and packaging.

2) What types of positive displacement pumps are commonly used in the pharmaceutical industry?

The pharmaceutical industry commonly uses several pumps, including diaphragm pumps, peristaltic pumps, and piston pumps. Each type is chosen based on its suitability for different applications, such as handling viscous fluids or sensitive materials.

3) What is the most common use of a positive displacement pump?

The most common use of a positive displacement pump is transferring fluids at a consistent rate, irrespective of the pressure in the system. This is crucial in applications where maintaining a precise flow rate is essential, such as in dosing or metering applications.

4) What is the purpose of a positive displacement pump in a fluid power system?

In fluid power systems, a positive displacement pump's purpose is to convert mechanical energy into fluid energy. This involves creating flow by moving fluid, which helps power various hydraulic systems.

5) What features make Positive Displacement Pumps a preferred choice in the pharmaceutical industry?

These pumps are preferred in the pharmaceutical industry for their ability to handle a wide range of viscosities and sensitive fluids and maintain a consistent flow. Their hygienic design, which meets high cleanliness standards, and their precision in fluid handling are also key reasons for their preference in this sector.